Review: Prevention of gastric cancer: When is treatment of Helicobacter pylori warranted?
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چکیده
منابع مشابه
The Role of Helicobacter Pylori Virulence Factors in Gastric Cancer
Introduction: Gastrointestinal (GI) cancers are considered among the most important causes of mortality and morbidity. Helicobacter pylori infection has been proven to be highly associated with the development of a variety of gastric diseases such as chronic gastritis, peptic ulcer disease (PUD), mucosa-associated lymphoid tissue (MALT), and gastric cancer (GC). To date, the exact role of the v...
متن کاملPrevention of Gastric Cancer: Eradication of Helicobacter pylori and Beyond
Although its prevalence is declining, gastric cancer remains a significant public health issue. The bacterium Helicobacter pylori is known to colonize the human stomach and induce chronic atrophic gastritis, intestinal metaplasia, and gastric cancer. Results using a Mongolian gerbil model revealed that H. pylori infection increased the incidence of carcinogen-induced adenocarcinoma, whereas cur...
متن کاملPrevention of gastric cancer by Helicobacter pylori eradication.
The evidence supporting the important role of Helicobacter pylori causing gastric cancer is getting stronger. The mechanisms by which H. pylori can influence the progression to severe changes in the gastric mucosa are under investigation. An increased gastric epithelial cell proliferation has been observed in individuals infected with H. pylori. This lifelong increased cell turnover is deemed t...
متن کاملDietary prevention of Helicobacter pylori-associated gastric cancer with kimchi
To prove whether dietary intervention can prevent Helicobacter pylori-induced atrophic gastritis and gastric cancer, we developed cancer preventive kimchi (cpKimchi) through special recipe and administered to chronic H. pylori-initiated, high salt diet-promoted, gastric tumorigenesis mice model. H. pylori-infected C57BL/6 mice were administered with cpKimchi mixed in drinking water up to 36 wee...
متن کاملHelicobacter pylori and gastric cancer.
Helicobacter pylori has been the subject of intense investigation since its culture from a gastric biopsy in 1982. From the beginning, this gram-negative bacterium has provoked the interest of bacteriologists, gastroenterologists, infectious disease specialists, cancer biologists, epidemiologists, pathologists, and pharmaceutical scientists. Pathologists were among the first groups of scientist...
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ژورنال
عنوان ژورنال: Therapeutic Advances in Gastroenterology
سال: 2008
ISSN: 1756-2848,1756-2848
DOI: 10.1177/1756283x08093567